Reference Material for National Reference Laboratories

Collection of reference material

A panel of reference material of pathogens included in the Annex IV, part 2 of Council Directive 2006/88/EC was created in 1997 by the EURL for distribution to National Reference Laboratories. This task is of a central importance in the duties of the EURL. Given the pivotal role of histology in diagnostic procedures for diseases of molluscs, a particular emphasis is given to histological blocs, sections and slides.


This library includes materials (parrafin blocks, stained slides, infected tissue, resin blocks for TEM) covering the main pathogens of molluscs found in Europe and more broadly in the World ( Bonamia ostreae, B. exitiosa, B. roughleyi, Marteilia refringens, M. sydneyi, Perkinsus olseni, P. marinus, Iridovirus, Herpesvirus, Haplosporidium nelsoni, H. costale, Mikrocytos mackini, Vibrio tapetis, Vibrio spp., Marteilioides chungmuensis, Xenohaliotis californiensis, etc...). Bacterial strains are also conserved in the EURL collections. Most of them are type strains of Vibrio species or Vibrio strains isolated from mortality outbreaks, including oyster summer mortality and abalone die off. The collection is continuously enriched with new reference material, requested on a regular basis from scientists publishing papers in the field of mollusc pathology.

A particular website created by Ifremer, the CNRS and the University of Brittany is devoted to a collection of pathogenic and non-pathogenic bacteria related to aquaculture of fish and shellfish: (in french).

EURL collection on CD

The collection of photos, created in 1999, has been included in a practical guide for diagnostic in histology established under a www format. This guide was burnt on CDs and distributed to participants of workshops and visitors. A new version (1.3) with more information and updated pictures was distributed to European National Reference Laboratories in June 2007.